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Maitake mushroom effects on liver serums and lipids

 

The Effect of Maitake Mushrooms on Liver Serum and Lipids



Alternative Therapies
September 1996 Volume 2 No. 5 Pages 62-66


[Abstract:]

The ability to prevent disturbances in lipid metabolism may contribute to a lessening of cardiovascular risk factors, especially in people whose diet consists of foods that are high in fats, sugars, and simple carbohydrates. It has been reported that some mushrooms in the Basidiomycetes class decrease serum cholesterol concentrations.

In 1964, Kaneda et al found that eritadenine in shiitake (Lentinus edodes) lowers serum cholesterol concentrations in rats. It also has been reported that hiratake (Pleurotus ostreatus) has serum cholesterol-lowering ability, and that mannentake (Ganoderma lucidum) lowers blood pressure and serum cholesterol concentration in spontaneously hypertensive rats.

Researchers also have discussed maitake's effects against hypertension and diabetes. In those experiments it was observed that increase in body weight was significantly less in maitake-fed groups than in basic-feed groups. In the following study, experimental animal models with hyperlipidemia were prepared in order to examine maitake's activity on the lipid metabolism in relation to the effect of inhibiting body weight increase by maitake.

Experimental rat models (5-weeks-old Sprague-Dawley rats) with hyperlipemia were prepared by feeding high-cholesterol feed containing sodium cholate and casein as a protein source. Dried maitake (Grifola frondosa) powder was mixed with the basic high-cholesterol feed and the serum lipids were periodically measured. Values of cholesterol, triglyceride and phospholipid in serum of rats in the maitake-feed group were suppressed by 0.3-0.8 times those in animals fed the basic feed, the latter values being close to those in rats given normal feed. The value of high-density lipoprotein (HDL) - cholesterol in serum which is generally reduced by the ingestion of high - cholesterol feed remained the level it was at the beginning of the experiment. Weights of extirpated liver and epididymal fat-pads were significantly less (0.6-0.7 times) than those in the basic feed group, indicating that maitake inhibits lipid accumulation in the body.

Liver lipids were also measured and the values were found to be decreased by maitake administration as true of serum lipid, suggesting maitake has an anti-liver lipid activity. Measurement of the amount of total cholesterol and bile acid in feces showed, the ratio of cholesterol-excretion had increased 1.8 times and bile acid-excretion 3 fold by maitake treatment. From these results, it is believed that maitake helps to improve the lipid metabolism as it inhibits both liver lipid and serum lipid, which are increased by the ingestion of high-fat feed.


The above information is provided for general educational purposes only. It is not intended to replace competent health care advice received from a knowledgeable healthcare professional. You are urged to seek healthcare advice for the treatment of any illness or disease.
Health Canada and the FDA (USA) have not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.
15 or 30 sachets per box
$45 or $85 per box

 

 

 Maitake ingredients 
Shiitake
Maitake
Oyster
Himmenmatustake
Woodear
Yun zhi
Ling zhi/Reishi
Cauliflower


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